SCHEMBL4366145

SCHEMBL4366145

CC(=O)C1=C(C)C=CCC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.36
MAOB P27338 1/20 0.36
IDO1 P14902 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912133 0.84 MAOA (0.36) MAOAMAOBIDO1
SCHEMBL11456623 0.80 MAOA (0.35) MAOAMAOB
SCHEMBL11448798 0.80 MAOA (0.35) MAOAMAOB
SCHEMBL17129800 0.79 MAOA (0.34) MAOAMAOBIDO1
SCHEMBL25418791 0.78 TSHR (0.32) MAOAMAOB
SCHEMBL11447991 0.77 MAOA (0.35) MAOAMAOB
SCHEMBL164856 0.77 MAOA (0.35) MAOAMAOB
SCHEMBL13966472 0.77 PTGS1 (0.33) MAOAMAOBL3MBTL1
SCHEMBL5980823 0.77 MAOA (0.35) MAOAMAOB
SCHEMBL11448674 0.77 MAOA (0.35) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4405323-B1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH & CIE (CH) 2026-01-14 EP claimed
US-20250034074-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2025-01-30 US claimed
EP-4405323-A1 PROCESS FOR PREPARING A CYCLIC DIENE Firmenich SA (CH) 2024-07-31 EP claimed
WO-2023094502-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2023-06-01 WO claimed
JP-4268806-B2 2009-05-27 JP claimed
EP-1395542-B1 CATALYTIC SYSTEM FOR ALDOL REACTIONS FIRMENICH & CIE (CH) 2006-08-16 EP claimed
US-6838575-B2 Catalytic system for aldol reactions FIRMENICH SA (CH) 2005-01-04 US claimed
JP-2004529190-A 2004-09-24 JP claimed
US-20040082818-A1 Catalytic system for aldol reactions FIRMENICH SA (CH) 2004-04-29 US claimed
EP-1395542-A1 CATALYTIC SYSTEM FOR ALDOL REACTIONS FIRMENICH SA (CH) 2004-03-10 EP claimed
WO-2002094755-A1 CATALYTIC SYSTEM FOR ALDOL REACTIONS FIRMENICH SA (CH) 2002-11-28 WO claimed
US-4172850-A CATALYTIC HYDROGENATION OF ACYCLCYCLOHEXADIENE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-10-30 US claimed
EP-4405323-B1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH & CIE (CH) 2026-01-14 EP disclosed
US-20250034074-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2025-01-30 US disclosed
EP-4405323-A1 PROCESS FOR PREPARING A CYCLIC DIENE Firmenich SA (CH) 2024-07-31 EP disclosed
WO-2023094502-A1 PROCESS FOR PREPARING A CYCLIC DIENE FIRMENICH SA (CH) 2023-06-01 WO disclosed
US-4157351-A 1-(2,6,6-Trimethyl-1,3-cyclohexadien-1-yl)-1,3-butanedione and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-06-05 US disclosed
US-4157350-A Process for preparing 1-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-1,3-butanedione and intermediates INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-06-05 US disclosed
US-4157350-A Process for preparing 1-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-1,3-butanedione and intermediates INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-06-05 US disclosed
US-3962311-A Preparation of cyclohexadiene compounds HOFFMANN-LA ROCHE INC. (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082818-A1 Catalytic system for aldol reactions AKR1B10, AGL, AKR1C2 MAOA 1158/4885MAOB 1305/4885IDO1 1111/4885
US-20250034074-A1 PROCESS FOR PREPARING A CYCLIC DIENE DHPS, FDFT1, CYP17A1 MAOA 780/4885MAOB 381/4885IDO1 3430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.