Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702852 | 0.87 | GABRA1 (0.50) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL7738539 | 0.87 | GABRA1 (0.50) | GABRA1GABRB2POLBKDM4EGAA | |
| Potassium Ion SCHEMBL7743976 | 0.87 | GABRA1 (0.50) | GABRA1GABRB2POLBKDM4EGAA | |
| Lithium Ion SCHEMBL7743757 | 0.87 | GABRA1 (0.50) | GABRA1GABRB2POLBKDM4EGAA | |
| Hydrochloric Acid SCHEMBL6040026 | 0.84 | GABRA1 (0.48) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL93161 | 0.74 | GABRA1 (0.69) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL10394690 | 0.71 | GABRA1 (0.65) | GABRA1GABRB2POLBKDM4EGAA | |
| SCHEMBL10415675 | 0.71 | GABRA1 (0.65) | GABRA1GABRB2POLBKDM4EGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL7086757 | 0.70 | GPR3 (0.38) | GABRA1GABRB2ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7089707 | 0.69 | GABRA1 (0.39) | GABRA1GABRB2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619106-B2 | Preparation of partially hydrogenated rac-ansa-metallocene complexes | BASELL POLYOLEFINE GMBH (DE) | 2009-11-17 | — | — | US | disclosed |
| US-20080200708-A1 | Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes | BASELL POLYOLEFINE GMBH (DE) | 2008-08-21 | — | — | US | disclosed |
| EP-1554295-B1 | PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2008-07-02 | — | — | EP | disclosed |
| EP-1554295-A1 | PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES | Basell Polyolefine GmbH (DE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037838-A1 | PREPARATION OF PARTIALLY HYDROGENATED RAC-ANSA-METALLOCENE COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200708-A1 | Preparation of Partially Hydrogenated Rac-Ansa-Metallocene Complexes | HRAS, RAP1A, NBAS | GABRA1 4311/4885GABRB2 4760/4885POLB 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.