SCHEMBL436630

SCHEMBL436630

C=CCc1ccc([Si](OCC)(OCC)OCC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
CYP3A4 P08684 3/20 0.48
TP53 P04637 2/20 0.48
TSHR P16473 2/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
PPARA Q07869 1/20 0.41
PTGS1 P23219 2/20 0.38
ALOX5 P09917 2/20 0.38
AR P10275 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
XDH P47989 1/20 0.36
GABRA1 P14867 6/20 0.35
GABRB2 P47870 6/20 0.35
MAPT P10636 3/20 0.35
CNR2 P34972 3/20 0.35
KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28578588 0.86 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2CYP3A4TP53TSHR
SCHEMBL23530247 0.83
SCHEMBL28588169 0.82 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2CYP3A4TP53TSHR
SCHEMBL436340 0.81 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2CYP3A4TP53TSHR
SCHEMBL20478197 0.79 NQO1 (0.35)
SCHEMBL50701 0.79 NQO1 (0.35)
SCHEMBL3482503 0.78 TP53 (0.39) ALDH1A1SMN1; SMN2TP53TSHRMAPK1
SCHEMBL3458351 0.78 TAAR1 (0.33)
SCHEMBL465240 0.77 ALDH1A1 (0.40) ALDH1A1CYP3A4CYP1A2CYP2D6HSD17B10
SCHEMBL431999 0.77 ALDH1A1 (0.44) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US claimed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US claimed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US claimed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US claimed
CN-112979876-B Branched conjugated diene polymer and method for producing same, method for producing rubber composition, and method for producing tire 旭化成株式会社 2023-09-08 CN disclosed
CN-112979876-A Branched conjugated diene polymer, method for producing same, method for producing rubber composition, and method for producing tire 旭化成株式会社 2021-06-18 CN disclosed
CN-103765313-A Photosensitive alkali-soluble silicone resin composition ASAHI KASEI E MATERIALS CORP 2014-04-30 CN disclosed
CN-101965542-B Photosensitive polyorganosiloxane composition ASAHI KASEI E MATERIALS CORP 2013-03-27 CN disclosed
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US disclosed
CN-101965542-A Photosensitive polyorganosiloxane composition ASAHI KASEI E MATERIALS CORP 2011-02-02 CN disclosed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US disclosed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US disclosed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN disclosed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN disclosed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US disclosed