SCHEMBL436340

SCHEMBL436340

C=CCc1ccc([Si](OC)(OC)OC)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
CYP3A4 P08684 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
TP53 P04637 1/20 0.57
ALOX15 P16050 1/20 0.57
TSHR P16473 1/20 0.57
ALOX12 P18054 1/20 0.57
PPARG P37231 2/20 0.47
PPARD Q03181 2/20 0.47
PPARA Q07869 1/20 0.47
PTGS1 P23219 2/20 0.43
ALOX5 P09917 2/20 0.43
AR P10275 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.43
GABRA1 P14867 3/20 0.39
GABRB2 P47870 3/20 0.39
XDH P47989 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436630 0.81 ALDH1A1 (0.48) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL5493559 0.81 ALDH1A1 (0.36) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL28578588 0.78 ALDH1A1 (0.46) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL675673 0.78 ALDH1A1 (0.46) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL3683779 0.77 ALDH1A1 (0.52) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL20584032 0.76 LTA4H (0.41) ALDH1A1CYP3A4SMN1; SMN2TSHRKMT2A
SCHEMBL173301 0.75 ALDH1A1 (0.64) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL50828 0.75 KDM4E (0.32) ALDH1A1SMN1; SMN2KDM4EMAPK1
SCHEMBL28588169 0.74 ALDH1A1 (0.42) ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15
SCHEMBL3098802 0.74 TP53 (0.40) ALDH1A1SMN1; SMN2TP53TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US claimed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US claimed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US claimed
CN-100494278-C Precusor solution of polyimide/silicon oxide composite its preparation process and manufactured composite material CHANGXING CHEMICAL INDUSTRY CO (CN) 2009-06-03 CN claimed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN claimed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US claimed
CN-112979876-B Branched conjugated diene polymer and method for producing same, method for producing rubber composition, and method for producing tire 旭化成株式会社 2023-09-08 CN disclosed
CN-112979876-A Branched conjugated diene polymer, method for producing same, method for producing rubber composition, and method for producing tire 旭化成株式会社 2021-06-18 CN disclosed
CN-104245846-A Polysiloxane composition having radical-crosslinkable group ASAHI KASEI E MATERIALS CORP 2014-12-24 CN disclosed
CN-103765313-A Photosensitive alkali-soluble silicone resin composition ASAHI KASEI E MATERIALS CORP 2014-04-30 CN disclosed
CN-101965542-B Photosensitive polyorganosiloxane composition ASAHI KASEI E MATERIALS CORP 2013-03-27 CN disclosed
US-8217388-B2 Curable organopolysiloxane composition and semiconductor device DOW CORNING TORAY COMPANY, LTD. (JP) 2012-07-10 US disclosed
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US disclosed
US-20080262158-A1 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY CO., LTD. (JP) 2008-10-23 US disclosed
EP-1781741-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO LTD (JP) 2008-08-27 EP disclosed
WO-2008023537-A1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD (JP) 2008-02-28 WO disclosed
EP-1781741-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER Dow Corning Toray Co., Ltd. (JP) 2007-05-09 EP disclosed
WO-2006011676-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO., LTD. (JP) 2006-02-02 WO disclosed
CN-1693367-A Forward solution of polyimide/silicon oxide composite its preparation process and manufactured composite from same CHANGXING CHEMICAL INDUSTRY CO (CN) 2005-11-09 CN disclosed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US disclosed