SCHEMBL436660

SCHEMBL436660

C=C(C)C(=O)OC(C)(C)C.C=CC(=C)C

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ALDH1A1 P00352 3/20 0.43
TP53 P04637 1/20 0.43
THRB P10828 1/20 0.31
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28204367 0.89 LMNA (0.42) TSHRALDH1A1TP53THRBDGAT1
Butadiene SCHEMBL28192911 0.89 ALDH1A1 (0.42) TSHRALDH1A1THRBDGAT1
SCHEMBL28298942 0.89 ALDH1A1 (0.50) TSHRALDH1A1THRBDGAT1
SCHEMBL33412 0.89 ALDH1A1 (0.50) TSHRALDH1A1THRBDGAT1
Acrylamide SCHEMBL28826478 0.88 ALDH1A1 (0.44) TSHRALDH1A1
SCHEMBL2157408 0.88 ALDH1A1 (0.38) TSHRALDH1A1TP53
SCHEMBL28064991 0.86 ALDH1A1 (0.48) TSHRALDH1A1THRBDGAT1
Ethylene SCHEMBL16830236 0.86 ALDH1A1 (0.48) TSHRALDH1A1THRBDGAT1
SCHEMBL28270676 0.86 ALDH1A1 (0.48) TSHRALDH1A1THRBDGAT1
Ammonia Solution, Strong SCHEMBL1022660 0.86 ALDH1A1 (0.48) TSHRALDH1A1THRBDGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180148530-A1 PHOSPHORYLATED POLYMERS BASF SE (DE) 2018-05-31 US disclosed
US-9920150-B2 Phosphorylated polymers BASF SE (DE) 2018-03-20 US disclosed
US-20160130381-A1 PHOSPHORYLATED POLYMERS BASF SE (DE) 2016-05-12 US disclosed
EP-1551885-B1 PROCESS TO MODIFY POLYMERIC MATERIALS 3M INNOVATIVE PROPERTIES CO (US) 2016-02-17 EP disclosed
US-8101711-B2 Process to modify polymeric materials and resulting compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-24 US disclosed
US-20100048819-A1 PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2010-02-25 US disclosed
US-7632916-B2 Thermally induced graft polymerization in an apparatus by shearing, devolatilization; grafting isoprene-t-butyl methacrylate copolymer with polyoxyethylene glycol methyl ether, forming methacrylic acid/anhydride monomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-15 US disclosed
EP-1551885-A2 PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS 3M Innovative Properties Company (US) 2005-07-13 EP disclosed
WO-2004013189-A2 PROCESS TO MODIFY POLYMERIC MATERIALS AND RESULTING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-12 WO disclosed
US-20040024130-A1 Process to modify polymeric materials and resulting compositions 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US disclosed