Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365542 | 1.00 | LTA4H (0.63) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL4801986 | 0.95 | TP53 (0.68) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL382171 | 0.95 | TP53 (0.68) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL382628 | 0.95 | TP53 (0.68) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL5820211 | 0.95 | TP53 (0.68) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL4798961 | 0.95 | TP53 (0.68) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL5814527 | 0.95 | TP53 (0.68) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL5819932 | 0.95 | TP53 (0.68) | LTA4HTP53TSHRPLA2G4BRAB9A | |
| SCHEMBL4367378 | 0.92 | KMT2A (0.55) | LTA4HTP53TSHRRAB9AGAA | |
| SCHEMBL4362617 | 0.92 | KMT2A (0.55) | LTA4HTP53TSHRRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749566-B1 | SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE | AIST (JP) | 2018-05-09 | — | — | EP | disclosed |
| US-9428809-B2 | Solid-phase carrier for aminated oligonucleotide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2016-08-30 | — | — | US | disclosed |
| US-20140187724-A1 | SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2014-07-03 | — | — | US | disclosed |
| EP-2749566-A1 | SOLID-PHASE CARRIER FOR AMINATED OLIGONUCLEOTIDE | National Institute of Advanced Industrial Science And Technology (JP) | 2014-07-02 | — | — | EP | disclosed |
| EP-1908829-B1 | OLIGONUCLEOTIDE PROBE | NAT INST OF ADVANCED IND SCIEN (JP) | 2014-01-08 | — | — | EP | disclosed |
| US-7491857-B2 | Oligonucleotide probe | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-02-17 | — | — | US | disclosed |
| US-20080227968-A1 | Oligonucleotide Probe | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-18 | — | — | US | disclosed |
| EP-1908829-A1 | OLIGONUCLEOTIDE PROBE | National Institute of Advanced Industrial Science and Technology (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227968-A1 | Oligonucleotide Probe | APEX1, RNGTT, RNASEH1 | LTA4H 3315/4885TP53 1749/4885TSHR 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.