Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.56 |
| ▸ | ITGB7 | P26010 | 11/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366748 | 0.94 | CYP3A4 (0.54) | ITGB1ITGA4ITGB7PSMB5CYP3A4 | |
| SCHEMBL11581256 | 0.88 | GFER (0.57) | ITGB1ITGA4ITGB7CYP3A4MAPK1 | |
| SCHEMBL11581254 | 0.88 | GFER (0.57) | ITGB1ITGA4ITGB7CYP3A4MAPK1 | |
| SCHEMBL4364556 | 0.85 | CTSL (0.63) | PSMB5CYP3A4MAPK1CTSL | |
| SCHEMBL4357884 | 0.84 | CTSL (0.55) | CYP3A4MAPK1GFERCTSL | |
| SCHEMBL4367288 | 0.83 | CTSL (0.58) | PSMB5CYP3A4MAPK1CTSL | |
| SCHEMBL4369419 | 0.83 | TSHR (0.61) | ITGB1ITGA4ITGB7PSMB5 | |
| SCHEMBL4363977 | 0.83 | TSHR (0.61) | ITGB1ITGA4ITGB7PSMB5 | |
| SCHEMBL27679186 | 0.81 | ITGB1 (0.62) | ITGB1ITGA4ITGB7PSMB5 | |
| SCHEMBL4362318 | 0.81 | ITGB1 (0.62) | ITGB1ITGA4ITGB7PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | claimed |
| US-9023809-B2 | Phenylalanine dipeptide derivatives, compositions and use thereof | THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUCTS OF GUIZHOU PROVINCE AND CHINESE ACADEMY OF SCIENCES (CN) | 2015-05-05 | — | — | US | disclosed |
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | DNPEP, PEPD, VIP | ITGB1 4794/4885ITGA4 4863/4885ITGB7 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.