Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 3/20 | 0.45 |
| ▸ | PRKX | P51817 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.45 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581254 | 1.00 | GFER (0.57) | GFERITGB1ITGA4ITGB7POLB | |
| SCHEMBL4366677 | 0.88 | ITGB1 (0.56) | GFERITGB1ITGA4ITGB7MAPK1 | |
| SCHEMBL24862961 | 0.82 | GFER (0.58) | GFERITGB1ITGA4ITGB7POLB | |
| SCHEMBL11582242 | 0.81 | ROCK2 (0.54) | POLBROCK2ROCK1NPC1ALDH1A1 | |
| SCHEMBL11582240 | 0.81 | ROCK2 (0.54) | POLBROCK2ROCK1NPC1ALDH1A1 | |
| SCHEMBL4366748 | 0.81 | CYP3A4 (0.54) | ITGB1ITGA4ITGB7SMONPC1 | |
| SCHEMBL24862886 | 0.80 | CAPN1 (0.57) | GFERITGB1ITGA4ITGB7POLB | |
| SCHEMBL11582078 | 0.78 | ROCK2 (0.70) | GFERPOLBROCK2PRKACAPRKX | |
| SCHEMBL11582081 | 0.78 | ROCK2 (0.70) | GFERPOLBROCK2PRKACAPRKX | |
| SCHEMBL14005607 | 0.77 | MAPK1 (0.56) | ROCK2PRKACAPRKXROCK1PRKG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097608-A | Anti-ulcerous tyrosine derivatives | DAIICHI SEIYAKU CO., LTD. (JA) | 1978-06-27 | — | — | US | disclosed |
| US-4057629-A | ANTIULCER | DAIICHI SEIYAKU CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |
| US-4025644-A | ANTIULCER | DAIICHI SEIYAKU CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |