Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 12/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366677 | 0.94 | ITGB1 (0.56) | CYP3A4MAPK1PSMB5ITGB1ITGA4 | |
| SCHEMBL4362318 | 0.86 | ITGB1 (0.62) | PSMB5ITGB1ITGA4ITGB7 | |
| SCHEMBL27679186 | 0.86 | ITGB1 (0.62) | PSMB5ITGB1ITGA4ITGB7 | |
| SCHEMBL4372161 | 0.83 | CTSL (0.61) | CYP3A4MAPK1PSMB5NPC1RAB9A | |
| SCHEMBL16993942 | 0.83 | ITGB1 (0.67) | ITGB1ITGA4ITGB7 | |
| SCHEMBL16993943 | 0.83 | ITGB1 (0.67) | ITGB1ITGA4ITGB7 | |
| SCHEMBL4364557 | 0.82 | CTSL (0.58) | CYP3A4MAPK1PSMB5NPC1RAB9A | |
| SCHEMBL4369254 | 0.81 | ALDH1A1 (0.58) | PSMB5ITGB1ITGA4ITGB7RAB9A | |
| SCHEMBL11581254 | 0.81 | GFER (0.57) | CYP3A4MAPK1ITGB1ITGA4ITGB7 | |
| SCHEMBL11581256 | 0.81 | GFER (0.57) | CYP3A4MAPK1ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | claimed |
| US-9023809-B2 | Phenylalanine dipeptide derivatives, compositions and use thereof | THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUCTS OF GUIZHOU PROVINCE AND CHINESE ACADEMY OF SCIENCES (CN) | 2015-05-05 | — | — | US | disclosed |
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | DNPEP, PEPD, VIP | CYP3A4 1134/4885MAPK1 2260/4885PSMB5 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.