Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371826 | 1.00 | CA1 (0.50) | CA1CA2MTNR1AMTNR1BGCGR | |
| SCHEMBL4367006 | 1.00 | CA1 (0.50) | CA1CA2MTNR1AMTNR1BGCGR | |
| SCHEMBL4369942 | 0.93 | CA1 (0.49) | CA1CA2MTNR1AMTNR1BGCGR | |
| SCHEMBL4371462 | 0.93 | CA1 (0.49) | CA1CA2MTNR1AMTNR1BGCGR | |
| SCHEMBL4366946 | 0.93 | CA1 (0.49) | CA1CA2MTNR1AMTNR1BGCGR | |
| SCHEMBL4367232 | 0.92 | MTNR1A (0.50) | MTNR1AMTNR1BALOX5OR51E2TSHR | |
| SCHEMBL4367939 | 0.92 | CA1 (0.52) | CA1CA2MTNR1AMTNR1BGCGR | |
| SCHEMBL4369186 | 0.92 | CA1 (0.52) | CA1CA2MTNR1AMTNR1BGCGR | |
| SCHEMBL4361914 | 0.92 | MTNR1A (0.50) | MTNR1AMTNR1BALOX5OR51E2TSHR | |
| SCHEMBL4361909 | 0.92 | MTNR1A (0.50) | MTNR1AMTNR1BALOX5OR51E2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444195-A2 | PROCESS FOR THE PREPARATION OF ALPHA-HYDROXYCARBOXYLIC ACID AMIDES | Syngenta Participations AG (CH) | 2004-08-11 | — | — | EP | claimed |
| WO-2003042166-A2 | PROCESS FOR PREPARATION OF α-HYDROXYCARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | claimed |
| US-7521579-B2 | Process for the preparation of alpha hydroxycarboxylic acid amides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| EP-1526128-B1 | Process the preparation of alpha-hydroxycarboxylic acid amides | SYNGENTA PARTICIPATIONS AG (CH) | 2007-01-03 | — | — | EP | disclosed |
| EP-1444195-B1 | PROCESS FOR THE PREPARATION OF ALPHA-HYDROXYCARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-08-10 | — | — | EP | disclosed |
| EP-1526128-A2 | Process the preparation of alpha-hydroxycarboxylic acid amides | Syngenta Participations AG (CH) | 2005-04-27 | — | — | EP | disclosed |
| US-20050014950-A1 | Process for the preparation of alpha hydroxycarboxylic acid amides | SYNGENTA CROP PROTECTION, INC. | 2005-01-20 | — | — | US | disclosed |
| EP-1444195-A2 | PROCESS FOR THE PREPARATION OF ALPHA-HYDROXYCARBOXYLIC ACID AMIDES | Syngenta Participations AG (CH) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003042166-A2 | PROCESS FOR PREPARATION OF α-HYDROXYCARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014950-A1 | Process for the preparation of alpha hydroxycarboxylic acid amides | HCAR1, HCAR3, HCAR2 | CA1 365/4885CA2 396/4885MTNR1A 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.