Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795607 | 0.91 | KIF11 (0.54) | KIF11KIF23 | |
| SCHEMBL4364755 | 0.84 | KIF11 (0.68) | KIF11KIF23 | |
| SCHEMBL4363439 | 0.80 | KIF11 (0.58) | KIF11 | |
| SCHEMBL4376313 | 0.79 | KIF11 (0.57) | KIF11 | |
| Hydrochloric Acid SCHEMBL4359893 | 0.79 | KIF11 (0.49) | KIF11 | |
| SCHEMBL4367361 | 0.79 | KIF11 (0.46) | KIF11KIF23 | |
| SCHEMBL4375118 | 0.78 | KIF11 (0.68) | KIF11KIF23 | |
| SCHEMBL4362694 | 0.78 | KIF11 (0.68) | KIF11KIF23 | |
| SCHEMBL4371805 | 0.76 | KIF11 (0.66) | KIF11KIF23 | |
| SCHEMBL4368933 | 0.76 | KIF11 (0.66) | KIF11KIF23 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482343-B2 | Compounds, methods and compositions | CYTOKINETICS, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20070135432-A1 | Compounds, methods and compositions | CYTOKINETICS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-7166595-B2 | Compounds, methods and compositions | CYTOKINETICS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040077662-A1 | Compounds, methods and compositions | CYTOKINETICS, INC. | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077662-A1 | Compounds, methods and compositions | ALPP, PCNA, MKI67 | KIF11 808/4885KIF23 418/4885 |
| US-20070135432-A1 | Compounds, methods and compositions | ALPP, PCNA, MKI67 | KIF11 808/4885KIF23 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.