Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 known ✓ | P08912 | 3/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 known ✓ | P08173 | 2/20 | 0.39 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GALR3 | O60755 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598354 | 0.98 | THRB (0.53) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL475871 | 0.98 | THRB (0.53) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Sulfuric Acid SCHEMBL11784028 | 0.91 | THRB (0.47) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL725843 | 0.90 | THRB (0.52) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Bromide SCHEMBL5250787 | 0.90 | THRB (0.59) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Sulfuric Acid SCHEMBL3256604 | 0.90 | THRB (0.46) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL10300016 | 0.88 | THRB (0.53) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL13791392 | 0.88 | THRB (0.61) | THRBTSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL3760085 | 0.87 | TSHR (0.58) | THRBTSHRCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8777416 | 0.87 | TSHR (0.58) | THRBTSHRCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775705-A | Preparation method of phospholipid membranization aggregate containing cholesterol | 哈尔滨工业大学 | 2025-04-08 | — | — | CN | claimed |
| CN-118751077-A | Hollow woven tube reinforced polyvinylidene fluoride hollow fiber membrane and post-treatment method thereof | 江苏艾乐膜科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-113171752-B | Method for eliminating biogenic amine by using metal organic framework material in fruit wine aging process | 鲁东大学 | 2023-01-10 | — | — | CN | claimed |
| CN-119775705-A | Preparation method of phospholipid membranization aggregate containing cholesterol | 哈尔滨工业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-118751077-A | Hollow woven tube reinforced polyvinylidene fluoride hollow fiber membrane and post-treatment method thereof | 江苏艾乐膜科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113171752-B | Method for eliminating biogenic amine by using metal organic framework material in fruit wine aging process | 鲁东大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-114426384-A | Method for treating oil sludge | 河南省高新技术实业有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-110437661-B | Antibacterial/antifouling/antifogging coating based on blend of quaternary ammonium salt and N-hydroxy acrylamide and preparation method thereof | 天津大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-109134318-B | Preparation method of 4-methylsulfonyl acetophenone and α -bromo-4-methylsulfonyl acetophenone | 江苏美迪克化学品有限公司 | 2020-04-17 | — | — | CN | disclosed |
| US-7504001-B2 | Method for producing paper and agent for improving yield | SEIKO PMC CORPORATION (JP) | 2009-03-17 | — | — | US | disclosed |
| WO-2008074702-A1 | METHOD FOR CROSS-COUPLING USING METAL NANOPARTICLES AS THE CATALYST | BASF SE (DE) | 2008-06-26 | — | — | WO | disclosed |
| US-20060011317-A1 | Method for producing paper and agent for improving yield | SEIKO PMC CORPORATION (JP) | 2006-01-19 | — | — | US | disclosed |
| EP-1500745-A1 | METHOD FOR PRODUCING PAPER AND AGENT FOR IMPROVING YIELD | Seiko PMC Corporation (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-0466261-B1 | Improved stabilization of dispersions of metal oxides and/or carbon black in water | AGFA GEVAERT NV (BE) | 1995-10-04 | — | — | EP | disclosed |
| US-5292591-A | Acrylate block copolymer | AGFA-GEVAERT, N.V. (BE) | 1994-03-08 | — | — | US | disclosed |
| US-5200456-A | Dispersant of block polymer using acrylate or methacrylate nitrogen cationic monomer | AGFA-GEVAERT, N.V. (BE) | 1993-04-06 | — | — | US | disclosed |
| EP-0466261-A1 | Improved stabilization of dispersions of metal oxides and/or carbon black in water | AGFA-GEVAERT N.V. (BE) | 1992-01-15 | — | — | EP | disclosed |
| US-4158726-A | HIGH MOLECULAR WEIGHT, WATER-SOLUBLE CATIONIC ACRYLIC OR METHACRYLIC ESTER POLYMERS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1979-06-19 | — | — | US | disclosed |