Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.37 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760085 | 1.00 | TSHR (0.58) | TSHRTHRBBBOX1HTTPOLB | |
| Hydrochloric Acid SCHEMBL27676876 | 0.93 | TSHR (0.64) | TSHRTHRBBBOX1HTTPOLB | |
| Iodide SCHEMBL28856832 | 0.93 | TSHR (0.59) | TSHRTHRBBBOX1HTTPOLB | |
| Sulfuric Acid SCHEMBL28088493 | 0.92 | TSHR (0.50) | TSHRTHRBBBOX1HTTPOLB | |
| Hydrochloric Acid SCHEMBL475871 | 0.89 | THRB (0.53) | TSHRTHRBBBOX1HTTPOLB | |
| SCHEMBL1598354 | 0.89 | THRB (0.53) | TSHRTHRBBBOX1HTTPOLB | |
| SCHEMBL9442198 | 0.88 | TSHR (0.46) | TSHRTHRBBBOX1HTTPOLB | |
| Bromide SCHEMBL4367449 | 0.87 | THRB (0.52) | TSHRTHRBBBOX1HTTPOLB | |
| Bromide SCHEMBL10890592 | 0.86 | TSHR (0.59) | TSHRTHRBBBOX1HTTPOLB | |
| SCHEMBL14335010 | 0.86 | TSHR (0.53) | TSHRTHRBBBOX1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119433981-A | Preparation method and application of bio-based plastic starch slurry with medium-temperature water solubility | 江苏新瑞贝生物科技股份有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119433981-A | Preparation method and application of bio-based plastic starch slurry with medium-temperature water solubility | 江苏新瑞贝生物科技股份有限公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-0812956-A1 | HIGH PERFORMANCE PAPER AND PROCESS FOR PRODUCING THE SAME | Oji Paper Co., Ltd. (JP) | 1997-12-17 | — | — | EP | disclosed |