Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28996091 | 0.86 | TSHR (0.64) | CA1CA2TSHRTP53PARP15 | |
| SCHEMBL14453801 | 0.81 | CA1 (0.56) | CA1CA2TSHRTP53PARP15 | |
| Terephthalic Acid SCHEMBL9341327 | 0.81 | TSHR (0.92) | CA1CA2TSHRTP53SRD5A2 | |
| SCHEMBL17226019 | 0.80 | PARP10 (0.70) | CA1CA2TSHRPARP15PARP10 | |
| SCHEMBL6746609 | 0.79 | TSHR (0.67) | CA1CA2TSHRTP53PARP15 | |
| SCHEMBL22281 | 0.79 | PARP10 (0.78) | CA1CA2TSHRTP53PARP15 | |
| Terephthalic Acid SCHEMBL9861713 | 0.79 | PARP10 (0.78) | CA1CA2TSHRTP53PARP15 | |
| SCHEMBL5581520 | 0.79 | PARP10 (0.78) | CA1CA2TSHRTP53PARP15 | |
| SCHEMBL766069 | 0.79 | PARP10 (0.78) | CA1CA2TSHRTP53PARP15 | |
| Terephthalic Acid SCHEMBL11858116 | 0.78 | TSHR (0.86) | CA1CA2TSHRTP53SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11117947-B2 | Double-acylated GLP-1 derivatives | NOVO NORDISK A/S (DK) | 2021-09-14 | — | — | US | disclosed |
| EP-2595977-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010802-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |
| US-7888450-B2 | Liquid crystal polymer and film thereof | FUJIFILM CORPORATION (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20090240022-A1 | LIQUID CRYSTAL POLYMER AND FILM THEREOF | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090054629-A1 | Inhibitors of Transthyretin Amyloid Fibril Formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-02-26 | — | — | US | disclosed |
| US-7312361-B2 | Inhibitors of transthyretin amyloid fibril formation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054629-A1 | Inhibitors of Transthyretin Amyloid Fibril Formation | TTR, TTPA, APOB | CA1 4014/4885CA2 4583/4885TSHR 1585/4885 |
| US-11117947-B2 | Double-acylated GLP-1 derivatives | GLP1R, SLC5A1, IAPP | CA1 2572/4885CA2 1248/4885TSHR 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.