Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.47 |
| ▸ | CCR2 | P41597 | 8/20 | 0.44 |
| ▸ | CCR9 | P51686 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718204 | 0.86 | GPR35 (0.49) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL9613337 | 0.84 | GPR35 (0.62) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL13802535 | 0.81 | PLA2G4A (0.51) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL28156828 | 0.79 | GPR35 (0.43) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL4370468 | 0.79 | ALDH1A1 (0.50) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL4363318 | 0.78 | PLA2G4A (0.52) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL4361805 | 0.77 | PLA2G4A (0.53) | GPR35CCR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL9613229 | 0.76 | GPR35 (0.48) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL9613230 | 0.76 | GPR35 (0.48) | GPR35CCR2CCR9MEN1KMT2A | |
| SCHEMBL12921290 | 0.75 | GPR35 (0.47) | GPR35CCR2CCR9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | disclosed |