SCHEMBL4367933

SCHEMBL4367933

COC(OC)c1ccccc1CC(C)C

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.45
GABRB2 P47870 2/20 0.45
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ACHE P22303 1/20 0.32
TSHR P16473 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
ELANE P08246 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4318969 0.85 KMT2A (0.45) KMT2A
SCHEMBL9184834 0.79 GABRA1 (0.52) GABRA1GABRB2HPGDCA1CA2
SCHEMBL6681972 0.79 GABRA1 (0.52) GABRA1GABRB2HPGDCA1CA2
SCHEMBL3415124 0.78 APOBEC3G (0.39) GABRA1TSHRL3MBTL1ALDH1A1CYP3A4
SCHEMBL9492902 0.75 GABRA1 (0.48) GABRA1GABRB2TSHRKMT2AALDH1A1
SCHEMBL873677 0.75 GABRA1 (0.54) GABRA1GABRB2HPGDCA1CA2
SCHEMBL9118442 0.75 GABRA1 (0.54) GABRA1GABRB2HPGDCA1CA2
SCHEMBL8558576 0.75 GABRA1 (0.48) GABRA1GABRB2TSHRELANE
SCHEMBL840750 0.75 GABRA1 (0.64) GABRA1GABRB2
SCHEMBL17864869 0.75 ESR1 (0.40) GABRA1GABRB2HPGDHTTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009059944-A1 ELECTROCHEMICAL METHOD FOR PRODUCING BENZALDEHYDE DIMETHYL ACETYLENE BASF SE (DE) 2009-05-14 WO disclosed