Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016313 | 0.80 | TLR8 (0.67) | TLR8SMN1; SMN2CASRLMNATSHR | |
| SCHEMBL5551899 | 0.79 | SMN1; SMN2 (0.70) | TLR8SMN1; SMN2USP2LMNATSHR | |
| SCHEMBL6756284 | 0.77 | TLR8 (0.49) | TLR8SMN1; SMN2CASRUSP2LMNA | |
| SCHEMBL9847099 | 0.74 | TLR8 (0.72) | TLR8SMN1; SMN2CASR | |
| SCHEMBL16486950 | 0.73 | TLR8 (1.00) | TLR8 | |
| Carbamic Acid SCHEMBL11050258 | 0.73 | TLR8 (0.57) | TLR8SMN1; SMN2CASRUSP2LMNA | |
| SCHEMBL29832214 | 0.73 | TLR8 (0.45) | TLR8SMN1; SMN2CASRUSP2LMNA | |
| SCHEMBL26107500 | 0.73 | TLR8 (0.45) | TLR8SMN1; SMN2CASRUSP2LMNA | |
| SCHEMBL25436133 | 0.72 | TLR8 (0.60) | TLR8SMN1; SMN2CASRTSHR | |
| SCHEMBL26111330 | 0.71 | GRM2 (0.51) | TLR8SMN1; SMN2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1789425-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | ExxonMobil Research and Engineering Company (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006012327-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2006-02-02 | — | — | WO | disclosed |
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | TLR8 3493/4885SMN1; SMN2 3442/4885CASR 2113/4885 |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | TLR8 3493/4885SMN1; SMN2 3442/4885CASR 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.