Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4239980 | 0.84 | DPP7 (0.59) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL541044 | 0.84 | TAAR1 (0.58) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL28945212 | 0.81 | TAAR1 (0.66) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL46769 | 0.81 | MLYCD (0.55) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL18901273 | 0.81 | TAAR1 (0.55) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL29988585 | 0.81 | MRGPRX4 (0.57) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL15129325 | 0.81 | TAAR1 (0.55) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL42728 | 0.81 | MRGPRX4 (0.57) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL11525399 | 0.80 | TAAR1 (0.64) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL2025172 | 0.79 | IDO1 (0.52) | TAAR1IDO1CYP3A4MAPTMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008045-B1 | ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS | ANTABIO SAS (FR) | 2018-05-09 | — | — | EP | disclosed |
| CN-102617397-B | Ortho-formyl aminobenzoyl hydrazide compound, preparation method thereof and application | UNIV CHINA AGRICULTURAL | 2015-04-22 | — | — | CN | disclosed |
| CN-102617397-A | Ortho-formyl aminobenzoyl hydrazide compound, preparation method thereof and application | UNIV CHINA AGRICULTURAL | 2012-08-01 | — | — | CN | disclosed |
| US-7713985-B2 | Adenosine Aa2 receptor antagonists | SCHERING CORPORATION (US) | 2010-05-11 | — | — | US | disclosed |
| US-7713985-B2 | Adenosine Aa2 receptor antagonists | SCHERING CORPORATION (US) | 2010-05-11 | — | — | US | disclosed |
| EP-2038285-B1 | ADENOSINE A2A RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| US-20080255156-A1 | ADENOSINE A2A RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LLC | 2008-10-16 | — | — | US | disclosed |
| US-20080255156-A1 | ADENOSINE A2A RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LLC | 2008-10-16 | — | — | US | disclosed |
| WO-2008002596-A2 | ADENOSINE A2A RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2008-01-03 | — | — | WO | disclosed |
| US-4845089-A | PESTICIDES, AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| US-4822810-A | 1-aralkyl-5-imino-pyrazole compounds, pesticidal composition and use | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-18 | — | — | US | disclosed |
| EP-0287854-A1 | 1-Aralkyl pyrazoles | BAYER AG (DE) | 1988-10-26 | — | — | EP | disclosed |
| EP-0245785-A2 | 1-Aralkyl pyrazoles | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255156-A1 | ADENOSINE A2A RECEPTOR ANTAGONISTS | ADORA3, ADORA2A, ADORA1 | TAAR1 102/4885IDO1 935/4885HTR2A 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.