Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 8/20 | 0.48 |
| ▸ | LOX | P28300 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375266 | 0.81 | ST14 (0.50) | LOXL2LOXMAOBST14SCN9A | |
| SCHEMBL24400400 | 0.79 | LOXL2 (0.40) | LOXL2LOXMAOBSCN9A | |
| SCHEMBL30689315 | 0.76 | KDM4E (0.50) | MAOBSCN7AKCNH2SCN9A | |
| SCHEMBL4372661 | 0.76 | KDM4E (0.50) | MAOBSCN7AKCNH2SCN9A | |
| SCHEMBL2567209 | 0.74 | KDM4E (0.57) | LOXL2LOXST14P2RX3 | |
| Hydrochloric Acid SCHEMBL3778622 | 0.73 | KDM4E (0.55) | LOXL2LOXMAOBST14 | |
| SCHEMBL4373280 | 0.73 | ST14 (0.52) | LOXL2LOXMAOBST14 | |
| SCHEMBL15832930 | 0.73 | LOXL2 (0.61) | LOXL2LOXMAOBST14ALOX5AP | |
| Hydrochloric Acid SCHEMBL1713787 | 0.72 | MAOB (0.50) | LOXL2LOXMAOBST14 | |
| Hydrochloric Acid SCHEMBL4369957 | 0.72 | MAOB (0.47) | MAOBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |