Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.47 |
| ▸ | LOX | P28300 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18233500 | 0.87 | LOXL2 (0.51) | ST14SCN9APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL24400400 | 0.85 | LOXL2 (0.40) | SCN9APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL24401094 | 0.84 | LOXL2 (0.41) | SCN9APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9900498 | 0.84 | SCN9A (0.49) | SCN9APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL4373280 | 0.82 | ST14 (0.52) | ST14LOXL2LOXMAOB | |
| SCHEMBL25383135 | 0.81 | ALDH1A1 (0.50) | SCN9APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9108961 | 0.81 | PLAAT3 (0.55) | SCN9APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL4368145 | 0.81 | LOXL2 (0.48) | ST14SCN9ALOXL2LOXMAOB | |
| SCHEMBL40545 | 0.81 | LOXL2 (0.53) | LOXL2LOXMAOBTRPV4 | |
| SCHEMBL29404783 | 0.81 | LOXL2 (0.53) | LOXL2LOXMAOBTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |