Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 12/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.42 |
| ▸ | LOX | P28300 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1713787 | 0.98 | MAOB (0.50) | ST14MAOBLOXL2LOX | |
| Hydrochloric Acid SCHEMBL4221868 | 0.88 | LOXL2 (0.49) | ST14MAOBLOXL2 | |
| SCHEMBL875696 | 0.83 | LTA4H (0.50) | — | |
| SCHEMBL9901279 | 0.83 | FAAH (0.36) | ST14MAOB | |
| SCHEMBL24400581 | 0.83 | THRB (0.39) | MAOBLOXL2LOX | |
| SCHEMBL4375266 | 0.82 | ST14 (0.50) | ST14MAOBLOXL2LOX | |
| SCHEMBL9103247 | 0.81 | FAAH (0.42) | — | |
| SCHEMBL1713357 | 0.80 | CACNA1B (0.39) | LOXL2 | |
| SCHEMBL922221 | 0.77 | MAOB (0.69) | ST14MAOB | |
| SCHEMBL9106578 | 0.76 | FAAH (0.37) | ST14MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |