SCHEMBL4368256

SCHEMBL4368256

O=C(O)c1ccc(C(F)(F)C(F)(F)C(F)F)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.53
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
EPHX2 P34913 1/20 0.42
CYP2C8 P10632 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
RARB P10826 1/20 0.41
RARG P13631 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
TYR P14679 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28412795 0.90 ALDH1A1 (0.49) SRD5A2TSHRALDH1A1HSD17B10RXRA
SCHEMBL9840095 0.83 TSHR (0.49) TSHRALDH1A1HSD17B10EPHX2CES2
SCHEMBL10575754 0.83 CES2 (0.39) SRD5A2TSHRALDH1A1CES2CES1
SCHEMBL26665249 0.80 SRD5A2 (0.57) SRD5A2TSHRTP53ALDH1A1HSD17B10
SCHEMBL30144875 0.79 SRD5A2 (0.61) SRD5A2TSHRTP53ALDH1A1RXRA
SCHEMBL3241556 0.79 SRD5A2 (0.61) SRD5A2TSHRTP53ALDH1A1RXRA
SCHEMBL16429445 0.79 SRD5A2 (0.61) SRD5A2TSHRTP53ALDH1A1RXRA
SCHEMBL873525 0.78 HSD17B10 (0.46) ALDH1A1HSD17B10RXRARXRBTDP1
SCHEMBL30144881 0.78 SRD5A2 (0.59) SRD5A2TSHRTP53ALDH1A1RXRA
SCHEMBL4860443 0.77 SRD5A2 (0.53) SRD5A2TSHRTP53ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023113273-A1 METAL-ORGANIC FRAMEWORK FOR COLLECTING KRYPTON OR XENON, AND APPARATUS FOR COLLECTING KRYPTON OR XENON, COMPRISING SAME 랩인큐브 주식회사 2023-06-22 WO claimed
EP-1519981-B1 PROTON-CONDUCTING MEMBRANE AND THE USE THEREOF PEMEAS GMBH (DE) 2006-06-28 EP claimed
EP-0254220-B1 PROCESS FOR THE PREPARATION OF 2.2-BISPHENYL HEXAFLUOROPROPANE HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-12 EP claimed
EP-0255887-A1 Process for the preparation of 2,2-bis(3-nitrophenyl)-hexa-fluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-17 EP claimed
EP-0254220-A1 Process for the preparation of 2.2-bisphenyl hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-27 EP claimed
CN-116454308-A Isolating film and application thereof 律胜科技股份有限公司 2023-07-18 CN disclosed
WO-2023113273-A1 METAL-ORGANIC FRAMEWORK FOR COLLECTING KRYPTON OR XENON, AND APPARATUS FOR COLLECTING KRYPTON OR XENON, COMPRISING SAME 랩인큐브 주식회사 2023-06-22 WO disclosed
US-20090297975-A1 TONER, DEVELOPER, TONER CONTAINER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD RICOH COMPANY LIMITED (JP) 2009-12-03 US disclosed
EP-0800563-A1 POLYMERS FOR USE IN OPTICAL DEVICES Cambridge Display Technology Limited (GB) 1997-10-15 EP disclosed
WO-1996020253-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 1996-07-04 WO disclosed
EP-0610385-A1 LOW THERMAL EXPANSION COEFFICIENT POLYIMIDES WITH IMPROVED ELONGATION. DU PONT (US) 1994-08-17 EP disclosed
EP-0601063-A1 FLUORINE-CONTAINING DIAMINES, POLYAMIDES, AND POLYIMIDES. DU PONT (US) 1994-06-15 EP disclosed
WO-1993009163-A1 LOW THERMAL EXPANSION COEFFICIENT POLYIMIDES WITH IMPROVED ELONGATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 WO disclosed
WO-1993004033-A1 FLUORINE-CONTAINING DIAMINES, POLYAMIDES, AND POLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-04 WO disclosed
EP-0255887-A1 Process for the preparation of 2,2-bis(3-nitrophenyl)-hexa-fluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-17 EP disclosed
EP-0254220-A1 Process for the preparation of 2.2-bisphenyl hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-27 EP disclosed