SCHEMBL873525

SCHEMBL873525

O=C(O)c1ccc(C(F)(F)C(F)(F)C(F)F)cc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
TDP1 Q9NUW8 2/20 0.41
CYP2C19 P33261 2/20 0.41
USP2 O75604 1/20 0.41
SORT1 Q99523 12/20 0.40
MEN1 O00255 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
KMT2A Q03164 1/20 0.40
GRM8 O00222 1/20 0.40
GRM6 O15303 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
DRD3 P35462 1/20 0.40
GRM4 Q14833 1/20 0.40
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28873804 0.87 RXRB (0.43) HSD17B10ALDH1A1KDM4EHPGDCYP2C19
SCHEMBL16626112 0.87 HSD17B10 (0.53) HSD17B10ALDH1A1KDM4EHPGDTDP1
SCHEMBL29405245 0.83 HSD17B10 (0.50) HSD17B10ALDH1A1KDM4EHPGDTDP1
SCHEMBL1503424 0.83 HSD17B10 (0.50) HSD17B10ALDH1A1KDM4EHPGDTDP1
SCHEMBL7093508 0.83 HSD17B10 (0.50) HSD17B10ALDH1A1KDM4EHPGDTDP1
SCHEMBL261962 0.83 HSD17B10 (0.50) HSD17B10ALDH1A1KDM4EHPGDTDP1
SCHEMBL4857659 0.83 FOLH1 (0.46) HSD17B10HPGDUSP2MEN1KMT2A
SCHEMBL4890609 0.83 POLB (0.51) HSD17B10ALDH1A1KDM4EHPGDTDP1
SCHEMBL9578190 0.81 HSD17B10 (0.49) HSD17B10ALDH1A1KDM4EHPGDTDP1
SCHEMBL28070239 0.81 ALDH1A1 (0.49) HSD17B10ALDH1A1KDM4EHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113045782-A Ultrahigh-light-shading polyimide composite film and preparation method thereof 南京精工新材料有限公司 2021-06-29 CN claimed
CN-112851982-A Polyimide film and preparation method thereof 南京精工新材料有限公司 2021-05-28 CN claimed
CN-112778552-A Preparation method of polyimide film 南京精工新材料有限公司 2021-05-11 CN claimed
EP-3257888-B1 POLYAMIC ACID, POLYIMIDE RESIN AND POLYIMIDE FILM KOLON INC (KR) 2019-09-04 EP claimed
WO-2018213121-A1 CO-CAST THIN FILM COMPOSITE FLAT SHEET MEMBRANES UOP LLC (US) 2018-11-22 WO claimed
WO-2008072914-A1 POLYIMIDE RESIN AND LIQUID CRYSTAL ALIGNMENT LAYER AND POLYIMIDE FILM USING THE SAME KOLON INDUSTRIES, INC. (KR) 2008-06-19 WO claimed
US-7022809-B2 Polyimides for anchoring liquid crystals, display devices including same and method for the preparation of said devices NEMOPTIC (FR) 2006-04-04 US claimed
US-5501941-A POLYMERS FOR MICROELECTRONICS FROM HEXAFLUOROISOPROPYLIDENEBIS PHTHALIC ACID, POLYMETHYLPHENYLENEDIAMINES AND BENZOPHENONE TETRACARBOXYLIC ACIDS AMOCO CORPORATION (US) 1996-03-26 US claimed
EP-0299785-B1 WEAR RESISTANT SOLID FILM LUBRICANTS, THEIR PREPARATION AND USE ETHYL CORPORATION (US) 1991-02-13 EP claimed
US-12227628-B2 Toughened composite materials capable of delamination propagation resistance CYTEC INDUSTRIES INC. (US) 2025-02-18 US disclosed
CN-118271841-A Resin film having single-layer or multi-layer polyimide layer and metal-clad laminate 日铁化学材料株式会社 2024-07-02 CN disclosed
WO-2024071909-A1 OPTICAL FILM AND DISPLAY DEVICE COMPRISING SAME 코오롱인더스트리 주식회사 2024-04-04 WO disclosed
US-11898009-B2 Polyimide, laminate, and electronic device including same UBE CORPORATION (JP) 2024-02-13 US disclosed
US-20240045329-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELECTRONIC COMPONENT, ANTENNA ELEMENT, SEMICONDUCTOR PACKAGE, AND COMPOUND TORAY INDUSTRIES, INC. (JP) 2024-02-08 US disclosed
US-5320935-A Method of forming a pattern from a photosensitive heat-resistant poly(amide)imide having hydroxyphenyl groups CHISSO CORPORATION (JP) 1994-06-14 US disclosed
EP-0592219-A1 Magnetic head for magneto-optical recording, and magneto-optical recording apparatus CANON KABUSHIKI KAISHA (JP) 1994-04-13 EP disclosed
WO-1993009163-A1 LOW THERMAL EXPANSION COEFFICIENT POLYIMIDES WITH IMPROVED ELONGATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-13 WO disclosed
WO-1993006151-A1 POLYIMIDE COPOLYMERS CONTAINING 3,3',4,4'-TETRACARBOXYBIPHENYL DIANHYDRIDE (BPDA) MOIETIES AMOCO CORPORATION (US) 1993-04-01 WO disclosed
WO-1993004033-A1 FLUORINE-CONTAINING DIAMINES, POLYAMIDES, AND POLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-04 WO disclosed
WO-1992017439-A2 PERFLUOROALKYLATED DIAMINOMESITYLENE AND POLYIMIDES THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-15 WO disclosed