SCHEMBL436835

SCHEMBL436835

CC=COC(C)Cc1ccc(N(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
MAPK1 P28482 3/20 0.42
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 1/20 0.42
KMT2A Q03164 2/20 0.40
ACACB O00763 1/20 0.38
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CALM1 P0DP23 1/20 0.36
APP P05067 4/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RELA Q04206 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438130 0.84 CALM1 (0.41) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL434882 0.84 MEN1 (0.43) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL436345 0.81 NPSR1 (0.45) ALDH1A1MAPK1TDP1CYP3A4KMT2A
SCHEMBL435293 0.74 SLC2A1 (0.42) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL435292 0.74 SLC2A1 (0.42) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL8244501 0.72 ALDH1A1 (0.58) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL13003654 0.71 ALDH1A1 (0.52) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL18896535 0.69 ALDH1A1 (0.54) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL7519177 0.69 TAAR1 (0.57) ALDH1A1MAPK1TSHRTDP1CYP3A4
SCHEMBL7519175 0.69 TAAR1 (0.57) ALDH1A1MAPK1TSHRTDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US claimed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US claimed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US claimed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US claimed
US-8101703-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD (TW) 2012-01-24 US disclosed
US-20100297455-A1 PRECURSOR SOLUTION FOR POLYIMIDE/SILICA COMPOSITE MATERIAL, ITS MANUFACTURE METHOD, AND POLYIMIDE/SILICA COMPOSITE MATERIAL HAVING LOW VOLUME SHRINKAGE ETERNAL CHEMICAL CO., LTD. 2010-11-25 US disclosed
US-7790828-B2 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. (CN) 2010-09-07 US disclosed
US-20050245715-A1 Precursor solution for polyimide/silica composite material, its manufacture method, and polymide/silica composite material having low volume shrinkage ETERNAL CHEMICAL CO., LTD. 2005-11-03 US disclosed