SCHEMBL4368398

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4372605	0.95	PLG (0.43)	KLKB1PLGPRSS1PRSS2PRSS3
	SCHEMBL4368539	0.92	KLKB1 (0.51)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4367199	0.91	CTSL (0.48)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4375873	0.89	FAAH (0.44)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4362260	0.89	KMT2A (0.47)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4364749	0.89	PLG (0.51)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4366363	0.89	ACACB (0.44)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4369703	0.88	KLKB1 (0.52)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4373706	0.88	CTSS (0.47)	ACACBKLKB1PLGPRSS1PRSS2
	SCHEMBL4362966	0.88	KLKB1 (0.52)	ACACBKLKB1PLGPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.