SCHEMBL4368416

SCHEMBL4368416

COC(C)(C)Cc1ccc(CCO)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 7/20 0.47
CYP4F2 P78329 6/20 0.47
PPARA Q07869 2/20 0.46
CA2 P00918 2/20 0.45
TDP1 Q9NUW8 1/20 0.41
SPHK2 Q9NRA0 1/20 0.38
ESR1 P03372 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4368420 0.80 KCNH2 (0.36) TDP1SPHK2ESR1TSHRALDH1A1
SCHEMBL1835580 0.79 ESR1 (0.61) CA2ESR1TSHRCYP3A4
SCHEMBL1671178 0.77 CA2 (0.50) CYP4A11CYP4F2PPARACA2TDP1
SCHEMBL1738833 0.75 IDO1 (0.40) ESR1KDM4EALDH1A1GAAMAPT
SCHEMBL4368413 0.75 ESR1 (0.40) TDP1ESR1TSHRALDH1A1CYP3A4
SCHEMBL8880437 0.74 CYP4A11 (0.54) CYP4A11CYP4F2PPARACA2CA1
SCHEMBL872871 0.74 SLC6A2 (0.54) PPARATSHRALDH1A1CYP3A4CYP1A2
SCHEMBL27541453 0.73 CA2 (0.46) CYP4A11CYP4F2PPARACA2TDP1
SCHEMBL40656 0.72 CA2 (0.77) CYP4A11CYP4F2PPARACA2TDP1
Ammonia Solution, Strong SCHEMBL27418091 0.71 SLC6A2 (0.50) PPARATSHRKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009059944-A1 ELECTROCHEMICAL METHOD FOR PRODUCING BENZALDEHYDE DIMETHYL ACETYLENE BASF SE (DE) 2009-05-14 WO disclosed