SCHEMBL4368420

SCHEMBL4368420

COC(C)(C)Cc1ccc(CCOCCc2ccc(CC(C)(C)OC)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.36
ESR1 P03372 2/20 0.33
CYP3A4 P08684 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
SPHK2 Q9NRA0 1/20 0.32
CYP19A1 P11511 2/20 0.32
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
SLC6A4 P31645 1/20 0.31
HRH1 P35367 1/20 0.31
HTR2B P41595 1/20 0.31
CHRNA4 P43681 1/20 0.31
SLC6A3 Q01959 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
LMNA P02545 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4368416 0.80 CYP4A11 (0.47) ESR1CYP3A4CYP1A2CYP2D6CYP2C9
SCHEMBL4368413 0.75 ESR1 (0.40) ESR1CYP3A4CYP1A2CYP2D6CYP2C9
SCHEMBL1835580 0.75 ESR1 (0.61) ESR1CYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL1738833 0.75 IDO1 (0.40) ESR1CYP1A2CYP2D6CYP2C19HTR2A
SCHEMBL872871 0.74 SLC6A2 (0.54) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL793588 0.72 KCNH2 (0.50) KCNH2LMNATSHR
SCHEMBL25827946 0.72 HRH3 (0.43) KCNH2ESR1TDP1CASR
Ammonia Solution, Strong SCHEMBL27418091 0.71 SLC6A2 (0.50) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL2846166 0.70 TAAR1 (0.61) TAAR1TDP1CALM1
SCHEMBL16563794 0.69 ALDH1A1 (0.45) SLC6A4SLC6A3ALDH1A1TSHRCASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009059944-A1 ELECTROCHEMICAL METHOD FOR PRODUCING BENZALDEHYDE DIMETHYL ACETYLENE BASF SE (DE) 2009-05-14 WO disclosed