Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4368630

Cc1c[nH]cn1.O=C(O)C(F)(F)F

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
NOTUM Q6P988 2/20 0.32
GABRR1 P24046 1/20 0.31
KDM4E B2RXH2 1/20 0.30
AGBL2 Q5U5Z8 1/20 0.30
MAPT P10636 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL27357935 0.84 NOTUM (0.37) NOTUMGABRR1KDM4EHCAR2
Succinic Acid SCHEMBL19134064 0.78 GABRR1 (0.39) NOTUMGABRR1KDM4E
4-Imidazolecarboxylic Acid SCHEMBL20482343 0.77 ASPH (0.36) HRH4HRH3KDM4EHCAR2
Ethane SCHEMBL15300165 0.76
SCHEMBL16694372 0.76
Iodide SCHEMBL13274496 0.76
Phosphoric Acid SCHEMBL6231502 0.75 FDPS (0.33)
Trifluoroacetic Acid SCHEMBL3641756 0.74 KMT2A (0.39) HRH4HRH3
Trifluoroacetic Acid SCHEMBL3826623 0.74 KDM4E (0.46) KDM4EMAPT
Trifluoroacetic Acid SCHEMBL30271697 0.74 MAPK1 (0.40) NOTUMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658396-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2025-12-10 EP claimed
WO-2024163644-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2024-08-08 WO claimed
EP-4658396-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
WO-2024163644-A1 BELT REACTOR MANUFACTURING PROCESS FOR OLIGOMER SYNTHESIS Arrowhead Pharmaceuticals, Inc. (US) 2024-08-08 WO disclosed
WO-2009021978-A2 COMPOUNDS CONTAINING CARBABORANE RESIDUES AND THE USE THEREOF IN MEDICINE, ESPECIALLY FOR USE IN TUMOUR THERAPY UNIVERSITÄT LEIPZIG (DE) 2009-02-19 WO disclosed
US-20060167241-A1 Method for synthesizing cyclic bisdinucleoside MITSUI CHEMICALS, INC. (JP) 2006-07-27 US disclosed
EP-1645561-A1 METHOD OF SYNTHESIZING CYCLIC BISDINUCLEOSIDE Mitsui Chemicals, Inc. (JP) 2006-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167241-A1 Method for synthesizing cyclic bisdinucleoside NSUN2, POLR2H, POLB HRH4 2773/4885HRH3 1552/4885NOTUM 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.