Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204336 | 0.91 | TLR8 (0.61) | TLR8SMN1; SMN2TSHRGAAL3MBTL1 | |
| SCHEMBL226014 | 0.83 | TLR8 (0.66) | TLR8SMN1; SMN2TSHRGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL29205404 | 0.80 | TLR8 (0.59) | TLR8SMN1; SMN2TSHRGAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL30281768 | 0.80 | TLR8 (0.59) | TLR8SMN1; SMN2TSHRGAAL3MBTL1 | |
| SCHEMBL227366 | 0.79 | TLR8 (0.61) | TLR8SMN1; SMN2TSHRGAAALDH1A1 | |
| SCHEMBL10005374 | 0.79 | TLR8 (0.71) | TLR8SMN1; SMN2TSHRGAAL3MBTL1 | |
| SCHEMBL1022300 | 0.78 | TLR8 (0.69) | TLR8SMN1; SMN2TSHRGAAHTT | |
| SCHEMBL229083 | 0.76 | POLB (0.61) | TLR8SMN1; SMN2TSHRGAAL3MBTL1 | |
| SCHEMBL629040 | 0.76 | TLR8 (0.67) | TLR8SMN1; SMN2TSHRGAAL3MBTL1 | |
| SCHEMBL2343059 | 0.76 | TLR8 (1.00) | TLR8SMN1; SMN2TSHRGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1789425-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | ExxonMobil Research and Engineering Company (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006012327-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2006-02-02 | — | — | WO | disclosed |
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | TLR8 3493/4885SMN1; SMN2 3442/4885TSHR 664/4885 |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | TLR8 3493/4885SMN1; SMN2 3442/4885TSHR 664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.