Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 7/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374780 | 0.76 | HTR2A (0.38) | HTR2AHTR2CHTR2BTUBB1FPR2 | |
| SCHEMBL25306691 | 0.76 | AOC3 (0.36) | AOC3EGFRLCKSMN1; SMN2 | |
| SCHEMBL30527763 | 0.76 | AOC3 (0.36) | AOC3EGFRLCKSMN1; SMN2 | |
| SCHEMBL4377263 | 0.76 | AOC3 (0.36) | AOC3FPR2PDE4DEGFRLCK | |
| SCHEMBL4372081 | 0.75 | ENPP1 (0.39) | HTR2AHTR2CHTR2BTUBB1FPR2 | |
| SCHEMBL24952758 | 0.73 | PDGFRB (0.38) | SMN1; SMN2CYP1A1CYP1B1 | |
| SCHEMBL1619631 | 0.72 | SMN1; SMN2 (0.52) | HTR2AHTR2CHTR2BTUBB1FPR2 | |
| SCHEMBL12093640 | 0.72 | TUBB1 (0.49) | HTR2AHTR2CHTR2BTUBB1PDE4D | |
| SCHEMBL21823505 | 0.72 | HTR2A (0.51) | HTR2AHTR2CHTR2BTUBB1FPR2 | |
| SCHEMBL31096259 | 0.72 | HTR2A (0.51) | HTR2AHTR2CHTR2BTUBB1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |