Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 7/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372081 | 0.81 | ENPP1 (0.39) | HTR2AHTR2CHTR2BFPR2TUBB1 | |
| SCHEMBL4369345 | 0.76 | AOC3 (0.43) | HTR2AHTR2CHTR2BFPR2TUBB1 | |
| SCHEMBL24501262 | 0.75 | ALDH1A1 (0.32) | TUBB1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL4372417 | 0.73 | HTR2A (0.35) | HTR2AHTR2CHTR2BFPR2TUBB1 | |
| SCHEMBL30128522 | 0.71 | PDE10A (0.31) | ALDH1A1MAPT | |
| SCHEMBL20594900 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL21932394 | 0.71 | PDE10A (0.31) | ALDH1A1MAPT | |
| SCHEMBL27592899 | 0.70 | ACHE (0.41) | TUBB1KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL21823585 | 0.69 | TUBB1 (0.44) | HTR2AHTR2CHTR2BFPR2TUBB1 | |
| SCHEMBL24501260 | 0.69 | ALDH1A1 (0.31) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |