Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374787 | 0.78 | TDP1 (0.38) | MAPTCA12CA1CA9 | |
| SCHEMBL25306691 | 0.77 | AOC3 (0.36) | AOC3GAAKDM4EALDH1A1CYP11B1 | |
| SCHEMBL30527763 | 0.77 | AOC3 (0.36) | AOC3GAAKDM4EALDH1A1CYP11B1 | |
| SCHEMBL4369345 | 0.76 | AOC3 (0.43) | AOC3EGFRLCKFPR2PDE4D | |
| SCHEMBL21823462 | 0.74 | CA3 (0.35) | GAAKDM4EALDH1A1GLAMAPT | |
| SCHEMBL1618282 | 0.71 | L3MBTL1 (0.42) | GAAKDM4EALDH1A1GLAMAPT | |
| SCHEMBL4376694 | 0.70 | ALDH1A1 (0.34) | GAAKDM4EALDH1A1GLAMAPT | |
| SCHEMBL31250383 | 0.68 | CHRNB2 (0.37) | FPR2 | |
| SCHEMBL25306413 | 0.68 | CHRNB2 (0.37) | FPR2 | |
| SCHEMBL15086906 | 0.67 | TAAR1 (0.40) | GAAKDM4EALDH1A1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009103950-A1 | FLUORINATED PYRIDIN-4-0NES | BTG INTERNATIONAL LIMITED (GB) | 2009-08-27 | — | — | WO | disclosed |