Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405871 | 0.88 | L3MBTL1 (0.56) | SMN1; SMN2L3MBTL1TDP1TUBB1KMT2A | |
| SCHEMBL2518861 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2L3MBTL1KMT2AHTR2AHTR2C | |
| SCHEMBL2035810 | 0.85 | L3MBTL1 (0.53) | SMN1; SMN2L3MBTL1TDP1TUBB1KMT2A | |
| SCHEMBL1547887 | 0.83 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1TDP1TUBB1KMT2A | |
| SCHEMBL2525316 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2L3MBTL1TUBB1KMT2AHTR2A | |
| SCHEMBL13617356 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL1627720 | 0.81 | NFE2L2 (0.50) | SMN1; SMN2L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL29669870 | 0.81 | NFE2L2 (0.50) | SMN1; SMN2L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL12093640 | 0.81 | TUBB1 (0.49) | L3MBTL1TDP1TUBB1KMT2AHTR2A | |
| SCHEMBL12719865 | 0.80 | L3MBTL1 (0.45) | L3MBTL1TDP1ALDH1A1HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011064789-A1 | IMPROVED PROCESS FOR THE PREPARATION OF HALO-DIALKOXYBENZENES | HIKAL LIMITED (IN) | 2011-06-03 | — | — | WO | disclosed |
| US-7928268-B2 | Process for producing 1,2-dialkoxy-3-fluorobenzene | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20100286451-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | ASAHI GLASS COMPANY, LIMITED | 2010-11-11 | — | — | US | disclosed |
| US-7786330-B2 | sulfonation, halogenation, deprotection, with 2-fluorophenol as starting material; industrial scale | ASAHI GLASS COMPANY, LIMITED (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20090227817-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | ASAHI GLASS COMPANY, LIMITED | 2009-09-10 | — | — | US | disclosed |
| EP-2055692-A1 | PROCESS FOR PRODUCING 1,2-DIALKOXY-3-FLUOROBENZENE | Asahi Glass Co., Ltd. (JP) | 2009-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227817-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | HAAO, HDHD5, AFF2 | SMN1; SMN2 4823/4885L3MBTL1 2854/4885TDP1 3515/4885 |
| US-20100286451-A1 | Process for producing 1,2-dialkoxy-3-fluorobenzene | HAAO, HDHD5, AFF2 | SMN1; SMN2 4823/4885L3MBTL1 2854/4885TDP1 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.