Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 7/20 | 0.52 |
| ▸ | CCR2 | P41597 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18247762 | 0.89 | GPR35 (0.56) | GPR35LTB4RLTB4R2KDM4EPOLB | |
| SCHEMBL700814 | 0.87 | KDM4E (0.67) | GPR35KDM4EPOLBPKMCCR2 | |
| SCHEMBL700511 | 0.85 | SRD5A2 (0.73) | GPR35LTB4RLTB4R2KDM4EPOLB | |
| SCHEMBL699774 | 0.82 | NTRK1 (0.56) | GPR35LTB4RLTB4R2KDM4EPOLB | |
| SCHEMBL1553069 | 0.79 | GPR35 (0.67) | GPR35KDM4EPOLBCCR2ALDH1A1 | |
| SCHEMBL9613337 | 0.79 | GPR35 (0.62) | GPR35KDM4EPOLBCCR2ALDH1A1 | |
| Ether SCHEMBL12466642 | 0.78 | KDM4E (0.57) | GPR35KDM4EPOLBPKMCCR2 | |
| SCHEMBL700700 | 0.78 | CCR2 (0.65) | GPR35CCR2ABCB11 | |
| SCHEMBL7378692 | 0.78 | ALDH1A1 (0.65) | GPR35KDM4EPOLBCCR2ALDH1A1 | |
| SCHEMBL708583 | 0.78 | MCL1 (0.65) | GPR35KDM4EPOLBPKMCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | disclosed |