Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 5/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501878 | 0.83 | TP53 (0.50) | PTPN1ALPLCNR1GPBAR1ALDH1A1 | |
| SCHEMBL27946184 | 0.80 | SLC6A3 (0.51) | PTPN1GPBAR1ABL1SLC6A3MAPT | |
| SCHEMBL28734830 | 0.73 | ABL1 (0.56) | ALPLABL1SLC6A3MAPTMRGPRX4 | |
| SCHEMBL4368062 | 0.73 | ALPL (0.49) | ALPLCNR1ABL1SLC6A3MAPT | |
| SCHEMBL5362212 | 0.73 | CNR1 (0.70) | CNR1 | |
| SCHEMBL16871335 | 0.73 | SLC6A3 (0.65) | ALPLCNR1ABL1SLC6A3MAPT | |
| SCHEMBL608814 | 0.72 | ABL1 (0.68) | ABL1MAPTKDM4EALDH1A1NR4A2 | |
| SCHEMBL4363906 | 0.72 | ABL1 (0.62) | ALPLABL1SLC6A3MAPTKDM4E | |
| SCHEMBL1919841 | 0.71 | ALPL (0.56) | ALPLCNR1ABL1SLC6A3MAPT | |
| SCHEMBL28816298 | 0.71 | ALPL (0.50) | ALPLCNR1SLC6A3MAPTMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |