Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.80 |
| ▸ | BCR | P11274 | 16/20 | 0.80 |
| ▸ | PRKCA | P17252 | 3/20 | 0.73 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.66 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.66 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.62 |
| ▸ | PRKCG | P05129 | 1/20 | 0.62 |
| ▸ | PRKCB | P05771 | 1/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.62 |
| ▸ | PRKCH | P24723 | 1/20 | 0.62 |
| ▸ | PRKCI | P41743 | 1/20 | 0.62 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.62 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533540 | 0.86 | ABL1 (0.71) | ABL1BCRPRKCACAMKK2 | |
| SCHEMBL29707254 | 0.86 | ABL1 (0.71) | ABL1BCRPRKCACAMKK2 | |
| SCHEMBL23798722 | 0.84 | ABL1 (0.66) | ABL1BCRPRKCAPRKD3PRKCG | |
| SCHEMBL3869178 | 0.84 | ABL1 (0.74) | ABL1BCRPRKCAPIK3CGCAMKK2 | |
| SCHEMBL4382247 | 0.84 | PDGFRB (0.71) | ABL1BCRPRKCAPIK3CGCAMKK2 | |
| SCHEMBL4377508 | 0.83 | ABL1 (0.73) | ABL1BCRPRKCAPIK3CGCAMKK2 | |
| SCHEMBL16795493 | 0.82 | ABL1 (0.64) | ABL1BCRPRKCAPRKD3PRKCG | |
| SCHEMBL7461093 | 0.82 | PRKCA (0.69) | ABL1BCRPRKCAPIK3CGCAMKK2 | |
| SCHEMBL4894119 | 0.82 | ABL1 (0.65) | ABL1BCRPRKCAPRKD3PRKCG | |
| SCHEMBL3864409 | 0.80 | ABL1 (0.66) | ABL1BCRPRKCAPIK3CGPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | disclosed |