Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.65 |
| ▸ | BCR | P11274 | 12/20 | 0.65 |
| ▸ | PRKCA | P17252 | 7/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.60 |
| ▸ | EGFR | P00533 | 5/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | PRKCG | P05129 | 1/20 | 0.55 |
| ▸ | PRKCB | P05771 | 1/20 | 0.55 |
| ▸ | PRKCH | P24723 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.55 |
| ▸ | JAK3 | P52333 | 1/20 | 0.55 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707254 | 0.87 | ABL1 (0.71) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL533540 | 0.87 | ABL1 (0.71) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL3004681 | 0.83 | ABL1 (0.75) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL29928272 | 0.83 | ABL1 (0.61) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL29855980 | 0.83 | ABL1 (0.63) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL29912657 | 0.83 | ABL1 (0.75) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL28401628 | 0.83 | ABL1 (0.63) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL23798722 | 0.83 | ABL1 (0.66) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL4382247 | 0.82 | PDGFRB (0.71) | ABL1BCRPRKCAPDGFRBPDGFRA | |
| SCHEMBL4370091 | 0.82 | ABL1 (0.80) | ABL1BCRPRKCAPRKCDSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840122-B1 | AMINOPYRIMIDINE COMPOUNDS AND THEIR SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL USE THEREOF | SUN PIAOYANG (CN) | 2013-08-28 | — | — | EP | disclosed |
| US-8183242-B2 | Aminopyrimidine compounds and their salts, process for preparation and pharmaceutical use thereof | Sun, Piaoyang (CN) | 2012-05-22 | — | — | US | disclosed |
| US-20080312251-A1 | Aminopyrimidine Compounds and Their Salts, Process for Preparation and Pharmaceutical Use Thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2008-12-18 | — | — | US | disclosed |
| EP-1840122-A1 | AMINOPYRIMIDINE COMPOUNDS AND THEIR SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL USE THEREOF | Sun, Piaoyang (CN) | 2007-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312251-A1 | Aminopyrimidine Compounds and Their Salts, Process for Preparation and Pharmaceutical Use Thereof | DPYD, PKN2, TYMP | ABL1 7/4885BCR 2529/4885PRKCA 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.