Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.71 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.71 |
| ▸ | ABL1 | P00519 | 14/20 | 0.69 |
| ▸ | BCR | P11274 | 13/20 | 0.69 |
| ▸ | PRKCA | P17252 | 7/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.57 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 3/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | PRKCG | P05129 | 1/20 | 0.55 |
| ▸ | PRKCB | P05771 | 1/20 | 0.55 |
| ▸ | PRKCH | P24723 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707254 | 0.87 | ABL1 (0.71) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL533540 | 0.87 | ABL1 (0.71) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL23798722 | 0.85 | ABL1 (0.66) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL4370091 | 0.84 | ABL1 (0.80) | ABL1BCRPRKCAPRKCDSRC | |
| SCHEMBL16795493 | 0.83 | ABL1 (0.64) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL4087589 | 0.83 | ABL1 (0.75) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL4894119 | 0.82 | ABL1 (0.65) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL210190 | 0.82 | ABL1 (0.76) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL3748107 | 0.81 | CAMK2D (0.62) | PDGFRBPDGFRAABL1BCRPRKCA | |
| SCHEMBL1655099 | 0.81 | ABL1 (1.00) | PDGFRBPDGFRAABL1BCRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | disclosed |