SCHEMBL4370150

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19344748	0.86	P2RX7 (0.50)	TYK2GAAALDH2ALDH1A1ITGB2
	SCHEMBL4377125	0.86	ALDH1A1 (0.56)	TYK2GAAALDH1A1HPGDFEN1
	SCHEMBL13479838	0.80	TYK2 (0.52)	TYK2UTS2RITGB1ITGA4ITGB7
	SCHEMBL24209849	0.79	JAK1 (0.59)	TYK2ALDH1A1HPGDFEN1OGG1
	SCHEMBL10557796	0.79	P2RX7 (0.51)	GAAALDH1A1HPGDFEN1P2RX7
	SCHEMBL12473715	0.79	ALDH1A1 (0.47)	TYK2ALDH1A1HPGDFEN1OGG1
	SCHEMBL10558954	0.79	ALDH1A1 (0.50)	ALDH1A1HPGDFEN1OGG1P2RX7
	SCHEMBL14726669	0.79	TYK2 (0.55)	TYK2UTS2RITGB1ITGA4ITGB7
	SCHEMBL4919855	0.79	TYK2 (0.55)	TYK2UTS2RITGB1ITGA4ITGB7
	SCHEMBL1397518	0.79	TSHR (0.51)	TYK2UTS2RGAAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.