Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2284909 | 0.86 | HTR6 (0.64) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL12569386 | 0.85 | HTR6 (0.64) | HTR6SMN1; SMN2TAAR1GHSRADRA1A | |
| Hydrochloric Acid SCHEMBL2554758 | 0.85 | HTR6 (0.62) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL6840091 | 0.85 | NR3C1 (0.54) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL246185 | 0.83 | ALDH1A1 (0.53) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL8867295 | 0.82 | NR3C1 (0.51) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL10652433 | 0.81 | NR3C1 (0.48) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL7902370 | 0.81 | PTGS1 (0.59) | NR3C1ALDH1A1SMN1; SMN2KEAP1POLB | |
| SCHEMBL5262193 | 0.81 | NR3C1 (0.56) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL14131241 | 0.81 | NR3C1 (0.50) | HTR6NR3C1ALDH1A1SMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012485-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2013-01-10 | — | — | US | disclosed |
| CN-101619038-A | Isoquinoline compound or salt thereof, medicinal composition, preparation method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2010-01-06 | — | — | CN | disclosed |
| EP-2124913-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | Novartis AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2009012375-A2 | SQUARATE KINASE INHIBITORS | WYETH (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2008077597-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012485-A1 | ORGANIC COMPOUNDS | DPP4, DPP3, DPP7 | HTR6 896/4885NR3C1 1501/4885ALDH1A1 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.