Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16417774 | 0.91 | MAPT (0.46) | ELANECES2CES1CA1CA2 | |
| SCHEMBL14012162 | 0.85 | ELANE (0.55) | ELANE | |
| SCHEMBL11596680 | 0.85 | ELANE (0.73) | ELANECES2CES1CA1CA2 | |
| SCHEMBL9954037 | 0.83 | ELANE (0.70) | ELANECES2CES1CA1CA2 | |
| SCHEMBL15431761 | 0.83 | ALDH1A1 (0.46) | ELANECA1CA2SMN1; SMN2CYP1A2 | |
| SCHEMBL3308809 | 0.82 | ELANE (0.52) | ELANEMAPTMAPK1RAB9AKMT2A | |
| SCHEMBL28985550 | 0.82 | ELANE (0.52) | ELANELMNAMAPTRAB9A | |
| SCHEMBL10778751 | 0.82 | ELANE (0.64) | ELANELMNASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL1197149 | 0.82 | ELANE (0.52) | ELANESMN1; SMN2MAPTMEN1RAB9A | |
| SCHEMBL833149 | 0.81 | ELANE (0.55) | ELANEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596062-B1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | ROHM & HAAS (US) | 2019-09-18 | — | — | EP | disclosed |
| US-10273314-B2 | Set-LRP polymerization of acrylates in the presence of acids | ROHM AND HAAS COMPANY (US) | 2019-04-30 | — | — | US | disclosed |
| US-20130245216-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-09-19 | — | — | US | disclosed |
| EP-2596062-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | Rohm and Haas Company (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012012705-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | ROHM AND HAAS COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |