SCHEMBL1197149

SCHEMBL1197149

CC(C)(Br)C(=O)Oc1ccc(C(C)(c2ccc(OC(=O)C(C)(C)Br)cc2)c2ccc(OC(=O)C(C)(C)Br)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 15/20 0.52
RAB9A P51151 3/20 0.44
MAPT P10636 2/20 0.44
NPC1 O15118 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14012162 0.83 ELANE (0.55) ELANEESR2
SCHEMBL15397425 0.83 ELANE (0.47) ELANERAB9AMAPTNPC1HTT
SCHEMBL5951756 0.82 ELANE (0.50) ELANERAB9AMAPTNPC1HTT
SCHEMBL16417774 0.82 MAPT (0.46) ELANERAB9AMAPTNPC1SMN1; SMN2
SCHEMBL437118 0.82 ELANE (0.53) ELANERAB9AMAPTHTTSMN1; SMN2
SCHEMBL18119838 0.81 ELANE (0.77) ELANEMAPTNPSR1
SCHEMBL3308809 0.80 ELANE (0.52) ELANERAB9AMAPTNPC1TDP1
SCHEMBL28985550 0.80 ELANE (0.52) ELANERAB9AMAPTTDP1L3MBTL1
SCHEMBL10778751 0.80 ELANE (0.64) ELANEMAPTSMN1; SMN2TDP1MEN1
SCHEMBL12938540 0.79 ELANE (0.47) ELANERAB9AMAPTNPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862789-B2 Polymerization of diene monomers UNIVERSITY OF CONNECTICUT (US) 2018-01-09 US claimed
US-20160369027-A1 POLYMERIZATION OF DIENE MONOMERS UNIVERSITY OF CONNECTICUT 2016-12-22 US claimed
WO-2015003137-A1 POLYMERIZATION OF DIENE MONOMERS UNIVERSITY OF CONNECTICUT (US) 2015-01-08 WO claimed
US-20230265346-A1 LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-08-24 US disclosed
US-20230159827-A1 LIQUID CRYSTAL COMPOSITION, FLUORINE-CONTAINING POLYMER, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-20230159827-A1 LIQUID CRYSTAL COMPOSITION, FLUORINE-CONTAINING POLYMER, OPTICALLY ANISOTROPIC LAYER, LAMINATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-05-25 US disclosed
US-9862789-B2 Polymerization of diene monomers UNIVERSITY OF CONNECTICUT (US) 2018-01-09 US disclosed
US-20160369027-A1 POLYMERIZATION OF DIENE MONOMERS UNIVERSITY OF CONNECTICUT 2016-12-22 US disclosed
WO-2015003137-A1 POLYMERIZATION OF DIENE MONOMERS UNIVERSITY OF CONNECTICUT (US) 2015-01-08 WO disclosed
US-8404788-B2 Atom transfer radical polymerization process CARNEGIE MELLON UNIVERSITY (US) 2013-03-26 US disclosed
US-20110218306-A1 ATOM TRANSFER RADICAL POLYMERIZATION PROCESS CARNEGIE MELLON UNIVERSITY (US) 2011-09-08 US disclosed
US-7893174-B2 Atom transfer radical polymerization process CARNEGIE MELLON UNIVERSITY (US) 2011-02-22 US disclosed
US-20090214605-A1 Hydrophilic Core Polymeric Micelles for the Delivery of Water-Soluble Compounds DE MONTREAL, UNIVERSITE (CA) 2009-08-27 US disclosed
US-20090214605-A1 Hydrophilic Core Polymeric Micelles for the Delivery of Water-Soluble Compounds DE MONTREAL, UNIVERSITE (CA) 2009-08-27 US disclosed
US-20070276101-A1 Atom Transfer Radical Polymerization Process CARNEGIE MELLON UINIVERSITY (US) 2007-11-29 US disclosed
US-20070155926-A1 Degradable polymers MATYJASZEWSKI KRZYSZTOF 2007-07-05 US disclosed
EP-1725590-A1 ATOM TRANSFER RADICAL POLYMERIZATION PROCESS CARNEGIE-MELLON UNIVERSITY (US) 2006-11-29 EP disclosed
US-20060160974-A1 Novel polyvinyl esters CELANESE VENTURES GMBH (DE) 2006-07-20 US disclosed
WO-2005087819-A1 ATOM TRANSFER RADICAL POLYMERIZATION PROCESS CARNEGIE MELLON UNIVERSITY (US) 2005-09-22 WO disclosed
WO-2004087777-A2 DEGRADABLE POLYMERS CARNEGIE MELLON UNIVERSITY (US) 2004-10-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090214605-A1 Hydrophilic Core Polymeric Micelles for the Delivery of Water-Soluble Compounds ABCB4, PAM, PGR ELANE 3771/4885RAB9A 3534/4885MAPT 1140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.