Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720334 | 0.78 | — | — | |
| SCHEMBL2804398 | 0.69 | TDP1 (0.46) | TSHRTDP1CYP3A4PSMD14ALDH1A1 | |
| SCHEMBL9243328 | 0.67 | NR1H2 (0.45) | TSHRTDP1CYP3A4PSMD14ALDH1A1 | |
| SCHEMBL689803 | 0.66 | — | — | |
| SCHEMBL8579309 | 0.65 | TDP1 (0.46) | TSHRTDP1CYP3A4ALDH1A1MAPK1 | |
| SCHEMBL65440 | 0.65 | ESR1 (0.58) | TSHRTDP1CYP3A4PSMD14ALDH1A1 | |
| SCHEMBL8505226 | 0.65 | TDP1 (0.46) | TSHRTDP1CYP3A4PSMD14ALDH1A1 | |
| SCHEMBL21439834 | 0.63 | MAPT (0.41) | TSHRTDP1CYP3A4PSMD14ALDH1A1 | |
| SCHEMBL710831 | 0.62 | ESR1 (0.37) | — | |
| SCHEMBL1172632 | 0.62 | MAPT (0.38) | TSHRTDP1CYP3A4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7627382-B2 | Medical devices with aromatic polyimide coating | LAKE REGION MANUFACTURING, INC. (US) | 2009-12-01 | — | — | US | disclosed |
| EP-1888164-A1 | MEDICAL DEVICES WITH AROMATIC POLYIMIDE COATING | LAKE REGION MANUFACTURING, INC. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127763-A1 | MEDICAL DEVICES WITH AROMATIC POLYIMIDE COATING | LAKE REGION MANUFACTURING, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| US-20060271135-A1 | Medical devices with aromatic polyimide coating | LAKE REGION MANUFACTURING, INC. (US) | 2006-11-30 | — | — | US | disclosed |