SCHEMBL65440

SCHEMBL65440

CC[Si](CC)(c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.58
AR P10275 1/20 0.43
ESR2 Q92731 1/20 0.43
TDP1 Q9NUW8 6/20 0.43
CYP3A4 P08684 5/20 0.43
ALDH1A1 P00352 3/20 0.43
TP53 P04637 1/20 0.43
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 3/20 0.41
GFER P55789 2/20 0.41
MAPK1 P28482 2/20 0.41
KIF11 P52732 1/20 0.41
PSMD14 O00487 1/20 0.41
RECQL P46063 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3775767 0.84 ALDH1A1 (0.48) ESR1ARESR2TDP1CYP3A4
SCHEMBL9243328 0.81 NR1H2 (0.45) ESR1TDP1CYP3A4ALDH1A1TP53
SCHEMBL29286065 0.78 LMNA (0.47) ESR1TDP1CYP3A4ALDH1A1MEN1
SCHEMBL218362 0.74 ESR1 (1.00) ESR1ARESR2TDP1CYP3A4
SCHEMBL2444645 0.72 ESR1 (0.56) ESR1ARESR2ALDH1A1TP53
SCHEMBL21722327 0.72 ESR1 (0.56) ESR1ARESR2STS
SCHEMBL3036362 0.72 CYP3A4 (0.46) ESR1ARESR2TDP1CYP3A4
Benzidine SCHEMBL25422776 0.71 TDP1 (0.73) TDP1CYP3A4ALDH1A1TP53MEN1
Benzidine SCHEMBL6160242 0.71 TDP1 (0.73) TDP1CYP3A4ALDH1A1TP53MEN1
Butane SCHEMBL2511845 0.70 MAPT (0.61) TDP1CYP3A4ALDH1A1TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3368198-B1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2022-07-06 EP claimed
CN-108348871-B Highly branched, non-crosslinked aerogels, method for the production thereof and use thereof 蓝移材料有限公司 2021-11-05 CN claimed
US-11130844-B2 Polyamide-imide precursor, polyamide-imide film, and display device comprising same KOLON INDUSTRIES, INC. (KR) 2021-09-28 US claimed
EP-3241860-B1 POLYAMIDE-IMIDE PRECURSOR, POLYAMIDE-IMIDE FILM, AND DISPLAY DEVICE COMPRISING SAME KOLON INC (KR) 2021-03-24 EP claimed
US-10626239-B2 Polymer aerogel with improved mechanical and thermal properties Blueshift Materials, Inc. (US) 2020-04-21 US claimed
CN-105315666-B Transparent polymer film, electronic device including the same, and composition 三星电子株式会社 2020-03-10 CN claimed
CN-106009664-B Compositions, composites prepared therefrom, and films and electronic devices including the same 三星电子株式会社 2020-02-04 CN claimed
WO-2018200838-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL HAVING MACROPORES, METHODS OF MAKING, AND USES THEREOF Blueshift Materials, Inc. (US) 2018-11-01 WO claimed
US-20180305514-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2018-10-25 US claimed
EP-3368198-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF Blueshift International Materials, Inc. (US) 2018-09-05 EP claimed
EP-1000108-A4 AQUEOUS POLYIMIDE PROCESS COMMW SCIENT IND RES ORG (AU) 2000-10-11 EP claimed
EP-1000108-A1 AQUEOUS POLYIMIDE PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-05-17 EP claimed
WO-1999006470-A1 AQUEOUS POLYIMIDE PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-11 WO claimed
EP-0712866-B1 Polymer scale deposition preventive agent SHINETSU CHEMICAL CO (JP) 1998-07-29 EP claimed
EP-0712866-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-22 EP claimed
US-5378774-A ADDITION POLYMERIZATION IN A VESSEL HAVING A COATING OF AN AMINO SUBSTITUTED AROMATIC COMPOUND, AN AROMATIC DIHYDRAZIDE COMPOUND, AN INORGANIC COLLOID AND A WATER SOLUBLE POLYMER ON ITS INNER WALL SURFACES SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-01-03 US claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
EP-0317943-A2 Polymers prepared from 4,4'-bis-[2-(3,4-(dicarboxyphenyl) hexafluoroisopropyl] diphenyl ether dianhydride HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed
US-4101487-A HEAT CURABLE AROMATIC DIAMINE-DIACID-AIAMIDE COMPOUND GENERAL ELECTRIC COMPANY (US) 1978-07-18 US claimed
US-4073788-A Partially imidized polyamide-acid polymers, aqueous coating compositions, coated wire and method, and partially imidized intermediate GENERAL ELECTRIC COMPANY (US) 1978-02-14 US claimed