Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727077 | 0.93 | CYP2C19 (0.66) | CYP2C19RAB9ACTSCLMNAALDH1A1 | |
| SCHEMBL934056 | 0.86 | CYP2C19 (0.70) | CYP2C19RAB9ACTSCLMNAALDH1A1 | |
| SCHEMBL1766985 | 0.84 | CYP2C19 (1.00) | CYP2C19RAB9ACTSCLMNAALDH1A1 | |
| SCHEMBL28997199 | 0.84 | CYP2C19 (0.72) | CYP2C19RAB9ACTSCLMNAALDH1A1 | |
| SCHEMBL8413466 | 0.82 | RAB9A (0.55) | CYP2C19RAB9ACTSCLMNAALDH1A1 | |
| SCHEMBL19699149 | 0.81 | CTSC (0.59) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 | |
| SCHEMBL2058609 | 0.81 | CTSC (0.59) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 | |
| SCHEMBL1631750 | 0.81 | CTSC (0.59) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28362983 | 0.79 | CTSC (0.58) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL7066923 | 0.79 | CTSC (0.58) | CYP2C19RAB9ACTSCSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084028-A2 | IMPROVED PROCESS FOR MANUFACTURING ANHYDROUS (E)-3-[2-BUTYL-1- {(4-CARBOXYPHENYL) METHYL}-1H-IMIDAZOLE-5-YL]-(THIOPHEN-2- YLMETHYL)PROP-2-ENOIC ACID METHANE SULFONATE | NEULAND LABORATORIES LTD (IN) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084028-A2 | IMPROVED PROCESS FOR MANUFACTURING ANHYDROUS (E)-3-[2-BUTYL-1- {(4-CARBOXYPHENYL) METHYL}-1H-IMIDAZOLE-5-YL]-(THIOPHEN-2- YLMETHYL)PROP-2-ENOIC ACID METHANE SULFONATE | NEULAND LABORATORIES LTD (IN) | 2009-07-09 | — | — | WO | disclosed |
| US-5169841-A | Enzyme inhibitors, hypotensive agents, high enteral bioauailability | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |