Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 14/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2058609 | 1.00 | CTSC (0.59) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| SCHEMBL1631750 | 1.00 | CTSC (0.59) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL2524346 | 0.98 | CTSC (0.58) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL7066923 | 0.98 | CTSC (0.58) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL28362983 | 0.98 | CTSC (0.58) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| SCHEMBL20543720 | 0.86 | CTSC (0.55) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL29780783 | 0.84 | CTSC (0.53) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| SCHEMBL9727077 | 0.83 | CYP2C19 (0.66) | CTSCRAB9ACYP2C19POLB | |
| SCHEMBL18023562 | 0.83 | CTSC (0.55) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 | |
| SCHEMBL19664147 | 0.83 | CTSC (0.55) | CTSCRAB9ACYP2C19SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345669-B2 | Urea derivatives and methods of use thereof | NodThera Limited (GB) | 2022-05-31 | — | — | US | disclosed |
| US-10669242-B2 | Clostridium difficile toxin inhibitors | Venenum Biodesign, LLC (US) | 2020-06-02 | — | — | US | disclosed |
| US-20200131141-A1 | CHEMICAL COMPOUNDS | NodThera Limited (GB) | 2020-04-30 | — | — | US | disclosed |
| US-20190194147-A1 | Novel Clostridium Difficile Toxin Inhibitors | Venenum Biodesign, LLC (US) | 2019-06-27 | — | — | US | disclosed |
| WO-2017214359-A1 | NOVEL CLOSTRIDIUM DIFFICILE TOXIN INHIBITORS | VENENUM BIODESIGN LLC (US) | 2017-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131141-A1 | CHEMICAL COMPOUNDS | IL1B, CASP1, IL1A | CTSC 355/4885RAB9A 1126/4885CYP2C19 2796/4885 |
| US-20190194147-A1 | Novel Clostridium Difficile Toxin Inhibitors | GABRA5, GABRA1, GABRA4 | CTSC 1715/4885RAB9A 3181/4885CYP2C19 157/4885 |
| US-10669242-B2 | Clostridium difficile toxin inhibitors | GABRA5, GABRA1, GABBR2 | CTSC 1526/4885RAB9A 3269/4885CYP2C19 106/4885 |
| US-11345669-B2 | Urea derivatives and methods of use thereof | IL1B, IL1A, NOD1 | CTSC 690/4885RAB9A 2527/4885CYP2C19 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.