Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | CTSC | P53634 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371675 | 0.93 | CYP2C19 (0.72) | CYP2C19RAB9ACTSCNPC1LMNA | |
| SCHEMBL7450943 | 0.85 | CYP2C19 (0.64) | CYP2C19RAB9ACTSCNPC1LMNA | |
| SCHEMBL8413466 | 0.85 | RAB9A (0.55) | CYP2C19RAB9ACTSCNPC1LMNA | |
| SCHEMBL19699149 | 0.83 | CTSC (0.59) | CYP2C19RAB9ACTSCPOLB | |
| SCHEMBL2058609 | 0.83 | CTSC (0.59) | CYP2C19RAB9ACTSCPOLB | |
| SCHEMBL1631750 | 0.83 | CTSC (0.59) | CYP2C19RAB9ACTSCPOLB | |
| Hydrochloric Acid SCHEMBL7066923 | 0.82 | CTSC (0.58) | CYP2C19RAB9ACTSCPOLB | |
| Hydrochloric Acid SCHEMBL28362983 | 0.82 | CTSC (0.58) | CYP2C19RAB9ACTSCPOLB | |
| Hydrochloric Acid SCHEMBL2524346 | 0.82 | CTSC (0.58) | CYP2C19RAB9ACTSCPOLB | |
| SCHEMBL16684110 | 0.82 | CYP2C19 (0.51) | CYP2C19RAB9ACTSCNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101215246-B | Method for preparing alpha-ketoxime acid ester | UNIV HEBEI SCIENCE & TECH | 2010-08-18 | — | — | CN | claimed |
| CN-101215246-A | Method for preparing alpha-ketoxime acid ester | UNIV HEBEI SCIENCE & TECH (CN) | 2008-07-09 | — | — | CN | claimed |
| CN-101215246-B | Method for preparing alpha-ketoxime acid ester | UNIV HEBEI SCIENCE & TECH | 2010-08-18 | — | — | CN | disclosed |
| CN-101215246-A | Method for preparing alpha-ketoxime acid ester | UNIV HEBEI SCIENCE & TECH (CN) | 2008-07-09 | — | — | CN | disclosed |
| US-5169841-A | Enzyme inhibitors, hypotensive agents, high enteral bioauailability | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |