Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055500 | 0.86 | KDM4E (0.39) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL4051867 | 0.81 | RXFP1 (0.40) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL22857366 | 0.76 | PDE4A (0.45) | ALDH1A1KMT2A | |
| SCHEMBL4240313 | 0.74 | PDE4A (0.40) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL13693694 | 0.73 | PDE4A (0.41) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL4018060 | 0.72 | MAOA (0.51) | KDM4EALDH1A1KMT2ACYP19A1 | |
| SCHEMBL4054310 | 0.71 | PDE10A (0.36) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL5022810 | 0.70 | TDP1 (0.45) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL5290305 | 0.70 | HTR2C (0.62) | KMT2AL3MBTL1 | |
| SCHEMBL29487580 | 0.70 | HTR2C (0.62) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115874-A2 | NOVEL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | MATRIX LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |