Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.61 |
| ▸ | ACE | P12821 | 5/20 | 0.60 |
| ▸ | CPA1 | P15085 | 5/20 | 0.60 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.60 |
| ▸ | GNPAT | O15228 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371868 | 1.00 | MME (0.61) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL13022186 | 1.00 | MME (0.61) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL8532925 | 0.92 | MME (0.61) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL13722204 | 0.90 | NAALAD2 (0.62) | MMEACECPA1ACE2GNPAT | |
| Afalanine SCHEMBL28767782 | 0.89 | CTSS (0.57) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL12064025 | 0.89 | MME (0.60) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL9073648 | 0.88 | ACE (0.62) | MMEACECPA1ACE2 | |
| SCHEMBL1081111 | 0.88 | GNPAT (0.73) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL6677690 | 0.88 | GNPAT (0.73) | MMEACECPA1ACE2GNPAT | |
| SCHEMBL5692056 | 0.88 | GNPAT (0.73) | MMEACECPA1ACE2GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709752-B2 | Process for producing dipeptides or dipeptide derivatives | KYOWA HAKKO BIO CO., LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-20120258490-A1 | PROCESS FOR PRODUCING DIPEPTIDES OR DIPEPTIDE DERIVATIVES | KYOWA HAKKO BIO CO., LTD. (JP) | 2012-10-11 | — | — | US | disclosed |
| US-8257943-B2 | In presence of ATP and peptidases | KYOWA HAKKO BIO CO., LTD. (JP) | 2012-09-04 | — | — | US | disclosed |
| CN-1973037-B | Process for producing dipeptide or dipeptide derivative | KYOWA HAKKO KOGYO KK | 2011-10-19 | — | — | CN | disclosed |
| EP-1616963-B1 | Process for producing dipeptides or dipeptide derivatives | KYOWA HAKKO BIO CO LTD (JP) | 2009-11-18 | — | — | EP | disclosed |
| US-20080213827-A1 | Process For Producing Dipeptides or Dipeptide Derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-09-04 | — | — | US | disclosed |
| EP-1767628-A1 | PROCESS FOR PRODUCING DIPEPTIDES OR DIPEPTIDE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |
| EP-1616963-A2 | Process for producing dipeptides or dipeptide derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-20050287627-A1 | Process for producing dipeptides or dipeptide derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213827-A1 | Process For Producing Dipeptides or Dipeptide Derivatives | DNPEP, PEPD, ANPEP | MME 194/4885ACE 372/4885CPA1 161/4885 |
| US-20050287627-A1 | Process for producing dipeptides or dipeptide derivatives | ADK, DNPEP, AMPD3 | MME 1221/4885ACE 1767/4885CPA1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.