Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138047 | 0.91 | TSHR (0.37) | ALDH1A1TSHR | |
| SCHEMBL5866441 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL6836609 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL2893058 | 0.85 | HPGD (0.33) | ALDH1A1 | |
| SCHEMBL27765915 | 0.83 | TSHR (0.45) | ALDH1A1TSHRTDP1 | |
| SCHEMBL15255052 | 0.83 | ALDH1A1 (0.35) | ALDH1A1TDP1 | |
| SCHEMBL273140 | 0.82 | DGKA (0.50) | ALDH1A1TSHR | |
| SCHEMBL8620268 | 0.81 | MGAM (0.32) | — | |
| SCHEMBL1902884 | 0.81 | — | — | |
| SCHEMBL27902952 | 0.81 | MGAM (0.48) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625580-B1 | Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-12-01 | — | — | US | disclosed |
| US-6224893-B1 | WOUND HEALING AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-01 | — | — | US | disclosed |
| EP-1011633-A1 | SEMI-INTERPENETRATING OR INTERPENETRATING POLYMER NETWORKS FOR DRUG DELIVERY AND TISSUE ENGINEERING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998052543-A1 | SEMI-INTERPENETRATING OR INTERPENETRATING POLYMER NETWORKS FOR DRUG DELIVERY AND TISSUE ENGINEERING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-11-26 | — | — | WO | disclosed |